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highly potent and selective histamine H1-receptor antagonist with anti-allergic activity
with IC50 of 5 nM (HTRF binding assays) and 20 nM (MTT proliferation assays)
The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model
Formula: C19H22Cl2N4
Narasin blocked NF-κB signaling via inhibition of IκBα phosphorylation at a lower concentration
Nalfurafine 061PEG17-Hydrazide highly potent and selective histamineNalfurafine (TRK 820) is a potent selective and orally active G protein biased kappa opioid receptor (KOR) agonist with high translational potential. Nalfurafine (TRK 820) enhances the therapeutic potential of MOR targeting analgesics, has the potential for uremic pruritis treatment. Product information CAS Number: 152657 84 6 Molecular Weight: 476. 56 Formula: C28H32N2O5 Chemical Name: (2E) N [(1S,5R,13R,14R,17S) 4 (cyclopropylmethyl) 10,17 dihydroxy
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