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plasma and brain exposures 0
DCLK1-IN-1 shows no significant activity against ERK5
there is no major decrease in mitochondrial import receptor subunit TOM20 homolog (TOMM20) or in the cytoskeleton protein β-actin
Formula: C16H25ClN2O4
β-Amyloid (31-35) increases the phosphorylation of biotinylated Aβ(1-40)
A-196 Size:Contact [email protected] for quotation plasma and brain exposures 0A 196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A 196 inhibits SUV4 20 biochemically in a substrate competitive manner. A 196 represents a first in class chemical probe of SUV4 20 to investigate the role of histone methyltransferases in genomic integrity. Product information CAS Number: 1982372 88 2 Molecular Weight: 359. 25 Formula: C18H16Cl2N4 Chemical Name: 6,7 dichloro N