rel-(R)-6-((R)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholin-3-one-d5 SN19023 PROTAC 3 causes BTK degradation

PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells

Taprenepag (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2

CF53 (Compound 28) binds to both the BD1 and BD2 domains of BRD2

3-benzodiazole-5-carboxamide trihydrochloride

Chemical Name: (3S)-N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl}-6-methoxy-3

rel-(R)-6-((R)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholin-3-one-d5 SN19023 PROTAC 3 causes BTK degradationProduct information CAS Number: 1292840 26 6 Molecular Weight: 332. 41 Formula: C19H21NO4 Chemical Name: (6R) 6 [(R) {2 [(1,1,2,2,2 H)ethoxy]phenoxy}(phenyl)methyl]morpholin 3 one Smiles: [2H]C([2H])([2H])C([2H])([2H])OC1=CC=CC=C1O[C@@H]([C@H]1CNC(=O)CO1)C1C=CC=CC=1 InChiKey: BXLPJKGEJVAHON CBXZRGHLSA N InChi: InChI=1S C19H21NO4 c1 2 22 15 10 6 7 11 16(15)24 19(14 8 4 3 5 9 14)17 12 20 18(21)13 23 17 h3 11,17,19H,2,12 13H2,1H3,(H,20,21) t17 ,19 m1 s1