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Gilteritinib - CAS# 1254053-43-4 Catalog No.:M8549-10 15-20H2/t21-

SKU: 52445317081

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Description

15-20H2/t21-

InChi: InChI=1S/C34H56N10O9/c1-18(2)13-23(30(49)40-22(11-8-12-39-34(37)38)29(48)44-26(33(52)53)16-27(36)46)42-31(50)24(14-19(3)4)43-32(51)25(41-28(47)21(35)17-45)15-20-9-6-5-7-10-20/h5-7

Bisquinolines

Highly stabilized amorphous 3-bis(4-methoxyphenyl)methylene-2-indolinone (TAS-301) in melt-adsorbed products with silicate compounds

Rod photoreceptor cell death is induced by okadaic acid through activation of PKC and L-type voltage-dependent Ca2+ channels and prevented by IGF-1

Gilteritinib - CAS# 1254053-43-4 Catalog No.:M8549-10 15-20H2/t21-Gilteritinib, also known as ASP2215, is a potent FLT3 AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3 ITD and FLT3 D835 mutations. In invitro, among the 78 tyrosine kinases tested, ASP2215 inhibited FLT3, LTK, ALK, and AXL kinases by over 50% at 1 nM with an IC50 value of 0. 29 nM for FLT3, approximately 800 fold more potent than for c KIT, the inhibition of which is linked to a potential risk of

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