Cot inhibitor-2 - CAS# 915363-56-3 rofen Calcium hydrate Smiles: COC(=O)CCC1C2=CC3=NC(=CC4NC(C=C5N=C(C=C(N2)C=1C)[C@]1(C)[C@@H](C(=CC=C15)C(=O)OC)C(=O)OC)=C(C)C=4C=C)C(C)=C3CCC(O)=O

Smiles: COC(=O)CCC1C2=CC3=NC(=CC4NC(C=C5N=C(C=C(N2)C=1C)[C@]1(C)[C@@H](C(=CC=C15)C(=O)OC)C(=O)OC)=C(C)C=4C=C)C(C)=C3CCC(O)=O

WYE-125132

Voriconazole is the first and only drug ever specifically indicated for their treatment by the FDA

also known as suberanilohydroxamic acid

InChi: InChI=1S/C22H23N3O4

Cot inhibitor-2 - CAS# 915363-56-3 rofen Calcium hydrate Smiles: COC(=O)CCC1C2=CC3=NC(=CC4NC(C=C5N=C(C=C(N2)C=1C)[C@]1(C)[C@@H](C(=CC=C15)C(=O)OC)C(=O)OC)=C(C)C=4C=C)C(C)=C3CCC(O)=OCot inhibitor 2 is a potent, selective and orally active cot (Tpl2 MAP3K8) inhibitor with an IC50 of 1. 6 nM. Cot inhibitor 2 inhibts TNF production in LPS stimulated human whole blood with an IC50 of 0. 3 M. Product information CAS Number: 915363 56 3 Molecular Weight: 539. 43 Formula: C26H25Cl2FN8 Synonym: 3 Quinolinecarbonitrile, 8 chloro 4 [(3 chloro 4 fluorophenyl)amino] 6 [[[1 (1 ethyl 4 piperidinyl) 1H 1,2,3 triazol 4 yl]methyl]amino] Chemical