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Formula: C23H24N4O4S
PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms
SAR405838 is a highly potent and selective MDM2 inhibitor
November 2013
InChi: InChI=1S/C18H30O7/c1-3-5-19-7-9-21-11-13-23-15-17-25-18-16-24-14-12-22-10-8-20-6-4-2/h1-2H
MW-150 hydrochloride 32524 Formula: C23H24N4O4SMW 150 hydrochloride (MW01 18 150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38 MAPK with a Ki of 101 nM. MW 150 hydrochloride (MW01 18 150SRM hydrochloride) inhibits the ability of the endogenous p38 MAPK to phosphorylate an endogenous substrate MK2 in activated glia. Product information CAS Number: 1923773 01 6 Molecular Weight: 417. 93 Formula: C24H24ClN5 Chemical Name: 6 (4 methylpiperazin 1 yl) 3 (naphthalen
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