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WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 60033 (2013) ACS Med Chem Lett

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Description

(2013) ACS Med Chem Lett

10(1 Suppl 1):1-19

but not cap-independent

Treatment of MCF7 and MDA-MB-231 breast cancer cells with KDM5-C70 significantly increased global levels of H3K4me3 while having little impact on H3K4me2/me1 or modifications regulated by other histone lysine demethylases

selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM

WAY-316606 hydrochloride - Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor. CAS# 1781835-02-6 60033 (2013) ACS Med Chem LettWAY 316606, CAS No. 1781835 02 6, is a novel potent and selective inhibitor of secreted frizzled related protein 1 (sFRP 1) with an IC50 ~ 0. 65 M. WAY 316606 prevents sFRP 1 from interacting with Wnt and thus increases Wnt signaling. WAY 316606 can increase total bone area in a murine calvarial organ culture assay. Product information CAS Number: 1781835 02 6 Molecular Weight: 484. 94 Formula: C18H20ClF3N2O4S2 Related CAS Number: 915759 45 4 (free

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