BET-BAY 002 - CAS# 1588521-78-1 124 and mutant forms of Flt3

and mutant forms of Flt3 and PDGFR alpha

induces apoptosis in NSCLC cells

Of the PI3K related kinases (PIKKs) tested

an orally bioavailable selective inhibitor of protein kinase CK2

Depletion of the central metabolite NAD leads to oncosis-mediated cell death

BET-BAY 002 - CAS# 1588521-78-1 124 and mutant forms of Flt3BET BAY 002 is a potent BET inhibitor; shows efficacy in a multiple myeloma model. Product information CAS Number: 1588521 78 1 Molecular Weight: 403. 86 Formula: C22H18ClN5O Synonym: BET BAY 002 Chemical Name: (7R) 9 (4 chlorophenyl) 3 methyl 7 [(5 methyl 1,3,4 oxadiazol 2 yl)methyl] 2,4,5 triazatricyclo[8. 4. 0. 0,]tetradeca 1(14),3,5,8,10,12 hexaene Smiles: CC1=NN=C2[C@H](CC3=NN=C(C)O3)C=C(C3=CC=CC=C3N12)C1C=CC(Cl)=CC=1 InChiKey: AGYIAWHWIUZNSD