JC-171 IN 3 Zibotentan binds selectively to the

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CAS Number: 1422389-91-0

JC-171 IN 3 Zibotentan binds selectively to theJC 171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8. 45 M for inhibiting LPS ATP induced interleukin 1 (IL 1) release from J774A. 1 macrophages. Product information CAS Number: 2112809 98 8 Molecular Weight: 384. 83 Formula: C16H17ClN2O5S Chemical Name: 5 chloro N {2 [4 (hydroxysulfamoyl)phenyl]ethyl} 2 methoxybenzamide Smiles: COC1=CC=C(Cl)C=C1C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NO InChiKey: KQRQPMUPYDOTCA UHFFFAOYSA N InChi: InChI=1S