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Vinflunine tartrate Ivabradine Hydrochloride IQ 1 thereby diminishes the

SKU: 48417184220

4.4
USD100.00 USD126.00

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Description

IQ 1 thereby diminishes the β-catenin/p300 interaction and prevents β-catenin coactivator switching from CBP to p300

18(15):4388-92

Smiles: O=C(NCC1C=CN=CC=1)[C@]12C[C@@]3(C[C@H](C1)C[C@@H](C3)C2)C1C=CC(Cl)=CC=1

InChi: InChI=1S/C16H21N3O4S2/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)25-9-5-18(6-9)16-17-3-4-24-16/h7-11

30675-13-9

Vinflunine tartrate Ivabradine Hydrochloride IQ 1 thereby diminishes theVinflunine is a bi fluorinated derivative of the semi synthetic vinca alkaloid vinorelbine with antitubulin, antineoplastic, and antiangiogenic activities. Vinflunine inhibits tubulin assembly without any stablization of assembled microtubules at concentrations comparable to those of other vinca alkaloids such as vincristine, vinblastine and vinorelbine; this effect on microtubule dynamics results in cell cycle arrest in mitosis and apoptosis.

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