K145 - CAS# 1309444-75-4 Size:Solid 2 mg InChi: InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18

InChi: InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18

InChi: InChI=1S/C31H29N5O3S2

Formula: C21H20N2O3S

also known as CPD77

Dirithromycin is a macrolide glycopeptide antibiotic

K145 - CAS# 1309444-75-4 Size:Solid 2 mg InChi: InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18K145 is a selective sphingosine kinase 2 (SphK2) inhibitor and anticancer agent. K145 inhibited the activity of SphK2 in a dose dependent manner with an IC50 of 4. 300. 06 M. K145 also exhibited inhibitory effects on the growth of U937 cells as well as apoptotic effects in U937 cells. K145 exhibits comparable in vivo anti tumor activity to tamibarotene, while concomitantly exhibiting less toxicity in this U937 xenograft cancer model. Product