TP-064 Catalog No.:M16833-C CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCCCN)C1SC=NC=1C)C(C)(C)C

CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCCCN)C1SC=NC=1C)C(C)(C)C

6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H

CAS Number: 70052-12-9

also known as PHA-739358

Formula: C25H26N2O5

TP-064 Catalog No.:M16833-C CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCCCN)C1SC=NC=1C)C(C)(C)CTP 064 is a potent and selective proteinarginine methyltransferase 4 (PRMT4; CARM1) inhibitor (IC50 <10 nM). TP 064 inhibits dimethylation of BAF155 (IC50 of 340 nM) and MED12 (IC50 of 43 nM). TP 064 is inactive against the other family members except for PRMT6 (IC50 of 1. 3 M). TP 064 has anticancer activities. Product information CAS Number: 2080306 20 1 Molecular Weight: 458. 60 Formula: C28H34N4O2 Chemical Name: N methyl N [(2 {1 [2