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LY-411575 (isomer 3) nserin 3-benzodiazol-1-yl)-N-(3-fluorophenyl)acetamido]-N-cyclohexyl-2-(2-methylphenyl)acetamide

SKU: 44683259699

4.8
USD120.00 USD147.00

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Description

3-benzodiazol-1-yl)-N-(3-fluorophenyl)acetamido]-N-cyclohexyl-2-(2-methylphenyl)acetamide

increase the percentage of polarized cells in an aged HSC population

8-dihydroxy-2H-1-benzopyran-2-one

VHL Ligand-Linker Conjugates 4 hydrochloride

5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylidene]-5-thia-2

LY-411575 (isomer 3) nserin 3-benzodiazol-1-yl)-N-(3-fluorophenyl)acetamido]-N-cyclohexyl-2-(2-methylphenyl)acetamideLY 411575 isomer 3, is an isomer of LY411575, which is a potent, cell permeable secretase inhibitor (IC50= 0. 078 nM 0. 082 nM (in membrane assay in cell based secretase assays)) and also inhibits Notch clevage (IC50= 0. 41 nM). Product information CAS Number: 2070009 28 6 Molecular Weight: 479. 48 Formula: C26H23F2N3O4 Synonym: LY411575 isomer 3 LY 411575 isomer 3 Chemical Name: (2R) 2 [(2R) 2 (3, 5 difluorophenyl) 2 hydroxyacetamido] N [(10S) 8

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