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VT-464 (R) is the R enantiomer of Seviteronel and is a potent inhibitor of CYP17 lyase (IC50: 69 nM for h-Lyase)
2011 Aug 19
-20oC for 3 month
InChiKey: ANCJYRJLOUSQBW-JJZGMWGRSA-N
CAN-08-4373
Sofosbuvir impurity N lolactone VT-464 (R) is the RSofosbuvir impurity N, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI 7977) is an inhibitor of HCV RNA replication, demonstrates potent anti hepatitis C virus activity. Product information CAS Number: 1394157 34 6 Molecular Weight: 501. 40 Formula: C20H25FN3O9P Chemical Name: methyl (2S) 2 {[(S) {[(2R,3R,4R,5R) 5 (2,4 dioxo 1,2,3,4 tetrahydropyrimidin 1 yl) 4 fluoro 3 hydroxy 4 methyloxolan 2
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