Brigatinib-analog - CAS# 1197958-12-5 nd Library of Histone Demethylase H-PGDS INHIBITOR I has no

H-PGDS INHIBITOR I has no code name

108 L/h) and this is largely attributed to extensive metabolism

PubMed Central PMCID: PMC2362948

Formula: C29H27F3N6O

24(17):4236-8

Brigatinib-analog - CAS# 1197958-12-5 nd Library of Histone Demethylase H-PGDS INHIBITOR I has noBrigatinib analog, CAS No. 1197958 12 5, is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib analog is structurally related to Brigatinib (AP 26113). Brigatinib analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and