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InChi: InChI=1S/2C5H4NOS
Smiles: COC1C(=CC=CC=1C1=NC2=CC=C3NN=CC3=C2C2CCCC=21)B(O)O
Smiles: [2H]C1([2H])C([2H])([2H])C([2H])([2H])N(C2CCN(CC2)C(=O)OC2C=C3C(CC)=C4CN5C(=CC6=C(COC(=O)[C@]6(O)CC)C5=O)C4=NC3=CC=2)C([2H])([2H])C1([2H])[2H]
5 min) are compared when the preparations sre superfused either by ACSF (n=8) or by the α2 adrenoceptor antagonist Piperoxane (50 μM
Marı A Maneiro
CCG-50014 Size:Contact [email protected] for quotation InChi: InChI=1S/2C5H4NOSCCG 50014 is the most potent against the regulator of G protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20 fold selective for RGS4 over other RGS proteins. CCG 50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid mediated analgesic effects in the mouse formalin test. Product information CAS Number: 883050 24 6