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Enzastaurin - CAS# 170364-57-5 0280 ATP secretion and thromboxane generation

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Description

ATP secretion and thromboxane generation

3-fold left shift of the glutamate CRC) at mGlu6 and antagonist activity (3

only one kinase other than mTOR kinase is identified with more than 50% inhibition (cFMS 57%

1155/2015/813816

and in vivo in monkeys and humans

Enzastaurin - CAS# 170364-57-5 0280 ATP secretion and thromboxane generationEnzastaurin, CAS No. 170364 57 5, also known as DB 102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF) stimulated neo angiogenesis. This agent may decrease tumor blood supply and so tumor burden. Product information CAS Number:

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