PI4KIII beta inhibitor 3 - CAS# 1245319-54-3 Catalog No.:M10227-2 InChi: InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28

InChi: InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28

It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt

Smiles: C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2C1=C(O)C1C(=O)C3=C(C=CC=C3C(=O)C=1C=2O)OC)/C(/CO)=N/NC(=O)CCCCCN1C(=O)C=CC1=O

808 nM (Human PKCε) Ki: 5

Kamimura M

PI4KIII beta inhibitor 3 - CAS# 1245319-54-3 Catalog No.:M10227-2 InChi: InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28PI4KIII beta inhibitor 3 is a novel and high effective PI4KIII inhibitor. Product information CAS Number: 1245319 54 3 Molecular Weight: 446. 53 Formula: C22H22N8OS Chemical Name: 4 [5 amino 2 (pyridin 3 yl) [1,3]thiazolo[5,4 d]pyrimidin 7 yl] N (4 methylphenyl)piperazine 1 carboxamide Smiles: CC1C=CC(=CC=1)NC(=O)N1CCN(CC1)C1N=C(N)N=C2SC(=NC=12)C1=CN=CC=C1 InChiKey: UWTRKIJAGTTXNM UHFFFAOYSA N InChi: InChI=1S C22H22N8OS c1 14 4 6 16(7 5 14)25 22(31)30