is potent and selective pan-RAF inhibitor with potential anticancer activity
Twenty-four hours after po administration
at more physiologically relevant concentrations (IC50 = 66 nM) when Flavopiridol is tested in the National Cancer Institute Development Therapeutics Program panel of 60 human tumor cell lines
Avosentan reduces albuminuria when added to standard treatment in people with type 2 diabetes and overt nephropathy but induces significant fluid overload and congestive heart failure
Low concentration (up to 25 μM) of Columbianadin induces apoptosis
Pedunculoside 3002 is potent and selective pan-RAFPedunculoside exerts lipid lowering effects partly through the regulation of lipogenesis and fatty acid oxidation. Product information CAS Number: 42719 32 4 Molecular Weight: 650. 84 Formula: C36H58O10 Chemical Name: (2S,3R,4S,5S,6R) 3,4,5 trihydroxy 6 (hydroxymethyl)oxan 2 yl (1R,2R,4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS) 8a,12b,14b trihydrogenio 1,10 dihydroxy 9 (hydroxymethyl) 1,2,6a,6b,9,12a hexamethyl