m-PEG16-azide 5126766 Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(N)=O

Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(N)=O

5 of 5 C/L858R mice displays nearly 80% reduction in tumor volume by magnetic resonance imaging MRI after therapy with AZD-9291

14-diamine

1-5H3/t15-

Development of dimeric modulators for anti-apoptotic Bcl-2 proteins

m-PEG16-azide 5126766 Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(N)=Om PEG16 azide is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information Molecular Weight: 761. 90 Formula: C33H67N3O16 Chemical Name: 49 azido 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47 hexadecaoxanonatetracontane Smiles: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N ] InChiKey: QWARPFMDFWZEFQ UHFFFAOYSA N InChi: InChI=1S C33H67N3O16 c1 37 4 5 39 8 9 41 12 13 43 16 17 45 20 21 47 24 25 49 28 29 51 32