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Aurora kinase inhibitor PHA-739358 binds to and inhibits the Aurora kinases
6 h against the Gram-positive strains but no PAE against Gram-negative strains
A recent study shows that induction of autophagy by STF-62247 increases sensitivity of RCC under hypoxic conditions to radiation in a VHL-dependent manner
53)54)24-14-22(62(46
CC(C)(N)C(=O)N[C@H](CC1=CNC2=CC=CC=C12)C(=O)N1C[C@](CC2C=CC=CC=2)(CCC1)C(=O)N(C)N(C)C
PC DBCO-PEG4-NHS ester 22814 Aurora kinase inhibitor PHA-739358 bindsPC DBCO PEG4 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055025 02 8 Molecular Weight: 945. 96 Formula: C47H55N5O16 Chemical Name: 1 {4 [3 ({14 [(3 {2 azatricyclo[10. 4. 0. 0,]hexadeca 1(16),4,6,8,12,14 hexaen 10 yn 2 yl} 3 oxopropyl)carbamoyl] 3,6,9,12 tetraoxatetradecan 1 yl}carbamoyl)propoxy] 5 methoxy 2 nitrophenyl}ethyl 2,5 dioxopyrrolidin 1 yl carbonate Smiles:
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