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Pretreatment with 1 μM Sildenafil citrate followed by serotonin stimulation leads to dramatic increase in OD value to 0
InChi: InChI=1S/C26H34O11/c1-10(2)6-15(28)37-18-20-25-9-35-26(20
FAAH is confirmed to be completely inhibited in mice treated with PF-04457845 at 1 and 10 mg/kg p
100(13):7971-6
PubMed PMID: 22366308
IM-12 - CAS# 1129669-05-1 Size:Solid 10 mg Pretreatment with 1 μM SildenafilIM 12 is a cell permeable indolylmaleimide that acts as a GSK 3 inhibitor. IM 12 is potent and selective enhances canonical Wnt signalling. IM 12 inhibits GSK 3 activity and subsequently increases catenin concentration significantly in hNPCs. When used to treat human neural progenitor cells, IM 12 promoted neuronal differentiation resulting in an increase of neuronal cells. Product information CAS Number: 1129669 05 1 Molecular Weight: 377. 41
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