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Smiles: CC1=CC=C(C=N1)C1=NC=C(Cl)C=C1C1C=CC(=CC=1)S(C)(=O)=O
Khojasteh SC
CHS 828 showed a synergistic effect with melphalan in 67%
PubMed PMID: 10576651
Right now it is in phase I clinical trials for patients with refractory advanced solid tumors
Retapamulin Catalog No.:M10666-10 Smiles: CC1=CC=C(C=N1)C1=NC=C(Cl)C=C1C1C=CC(=CC=1)S(C)(=O)=ORetapamulin, also known as SB 275833, is a newer topical agent of pleuromutilin class approved by the Food and Drug Administration for treatment of impetigo in children. It has been demonstrated to have low potential for the development of antibacterial resistance and a high degree of potency against poly drug resistant Gram positive bacteria found in skin infections including Staphylococcus aureus strains. The drug is safe owing to low systemic
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