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5 cell line
PubMed Central PMCID: PMC3706837
Formula: C16H21ClIN3O4S
CAS Number: 1146963-51-0
Smiles: CN1CCN(CC1)C1=CC=C(C=C1NC(=O)C1=CNC(=O)C=C1C(F)(F)F)C1=CC(CN2CCOCC2)=CC=C1
YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 5 cell lineYM 155, CAS No. 781661 94 7, is a novel survivin suppressant with an IC50 of 0. 54 nM for the inhibition of survivin promoter activity. Sepantronium bromide, also known as YM 155, is a small molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and
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