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dose-dependent reduction of phosphorylation of FGFR4 signaling pathway components
and inhibits migration and invasion
Formula: C14H20N6O5S
69(15):6208-15
tumor growth inhibition increases with increased exposure of the compound and that tumor regressions could only be achieved when the compound exposure consistently exceeded 90% of c-MET inhibition
A66 - CAS# 1166227-08-2 Catalog No.:M7134-10 dose-dependent reduction of phosphorylation ofA66, CAS No. 1166227 08 2, is a potent and highly selective p110 inhibitor with IC50 of 32 nM in a cell free assay, >100 fold selectivity for p110 over other class I PI3K isoforms. A66 blocks phosphoinositide 3 kinase signalling and tumour growth in certain cell types. Product information CAS Number: 1166227 08 2 Molecular Weight: 393. 53 Formula: C17H23N5O2S2 Synonym: A66 A 66 A 66 Chemical Name: (S) N1 (2 (tert butyl) 4' methyl [4,5' bithiazol] 2'
US$ 4750.00
US$ 65.00
US$ 3600.00