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InChiKey: MREBEPTUUMTTIA-PCLIKHOPSA-N
Jacobsen TA
PubMed Central PMCID: PMC5227137
SF-1670 (500 nM)–pretreated neutrophils show nearly 70% higher (maximal) superoxide production than untreated neutrophils
Smiles: C[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)C#C
SB-269970 Hydrochloride - CAS# 261901-57-9 Size:Solid 2 mg InChiKey: MREBEPTUUMTTIA-PCLIKHOPSA-NSB269970 HCl is a potent 5 HT7A antagonist (pKi = 8. 9) that demonstrates >50 fold binding selectivity over 5 HT5A and >250 fold selectivity over 5 HT1, 5 HT2, 5 HT4, 5 HT6, adrenergic 1, dopamine D2, and dopamine D3 receptors. It is also reported to block adrenergic 2 receptors in guinea pig vas deferens. SB 269970 has been used to target the 5 HT7 receptor in the study of schizophrenia like cognitive deficits. Product information CAS Number: 261901