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ONO-4059 (analog) or modulator-1 ISO-1 has CAS#478336-92-4

SKU: 30907609070

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Description

ISO-1 has CAS#478336-92-4

Formula: C20H26N4O5S

44)45)13-23(35)29(19)33(31)41)18-4-6-26(16(2)8-18)38-40-32-28(58(52

is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation

ClH/c1-2-3-5-14(10

ONO-4059 (analog) or modulator-1 ISO-1 has CAS#478336-92-4ONO 4059 analog is the analog of ONO 4059, ONO 4059 is a highly potent and selective Btk inhibitor. IC50 value: sub nM range Target: Btkin vitro: ONO 4059 is a selective, once daily, oral inhibitor of BTK, which has been shown to play a role in the survival and proliferation of malignant B cells. ONO 4059 shows a favourable safety profile along with promising efficacy in this difficult to treat patient population. in vivo: ONO 4059 has demonstrated

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