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1H3/b18-9+
InChi: InChI=1S/C23H22FN3O4S/c1-14-18(5-7-20(22(14)24)32(2
InChi: InChI=1S/C16H28N2O4
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
acting via the HIF-1α system
Topotecan Hydrochloride Size:Solid 2 mg 1H3/b18-9+Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I DNA covalent complexes, inhibiting religation of topoisomerase I mediated single strand DNA breaks and producing potentially lethal double strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline based alkaloid
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