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Lapatinib Size:Solid 10 mg H2O/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23

SKU: 30551566570

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Description

H2O/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23

2-dimethylpropanamido}-4-(2-methylphenyl)pyridin-2-yl)-1-methylpiperazin-1-ium-1-olate

GS5734-metabolite

InChi: InChI=1S/C38H69NO13/c1-15-26-38(10

Formula: C22H24Cl2N2O4

Lapatinib Size:Solid 10 mg H2O/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23Lapatinib is a synthetic, orally active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk 1 and 2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this

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