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The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation
It also prevents viral replication of hepatitis C
AZD1981 displaced radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8
3-dihydrofuran-3-one
Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptors antagonist
SKF-83566 capone Sodium Salt The selective cyclooxygenase-2 inhibitor SC-236SKF 83566 is a potent, blood brain permeable and orally active D1 like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5 HT2 receptor (Ki=11 nM). SKF 83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5. 7 M. SKF 83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF 83566 can be used for research of parkinsons
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