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It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium
is a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee
Formula: C25H25F3N2O2
Yoshikawa S
PubMed PMID: 23987060
SP600125 345541 It can inhibited phenylephrine- andSP 600125 is a specific JNK inhibitor. SP600125 kills p53 deficient cells more efficiently than their p53 proficient counterparts, in vitro. Similar observations were obtained in vivo, in mice carrying p53 deficient and proficient human xenografts. Product information CAS Number: 129 56 6 Molecular Weight: 220. 23 Formula: C14H8N2O Synonym: SP 600125 SP 600125 Chemical Name: dibenzo[cd, g]indazol 6(2H) one Smiles: O=C1C2=CC=CC=C2C2=NNC3=CC=CC1=C32
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