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Phthalimide-PEG3-C2-OTs Catalog No.:M14332-2 19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide

SKU: 28577633231

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Description

19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide

is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR)

InChi: InChI=1S/C12H8N4O6S/c13-23(21

Smiles: OC1C(I)=C(C(I)=CC=1I)C(O)=O

Williams D

Phthalimide-PEG3-C2-OTs Catalog No.:M14332-2 19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamidePhthalimide PEG3 C2 OTs (Compound 5) is a PROTAC linker, which refers to the PEGs composition. Phthalimide PEG3 C2 OTs can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target proteins. Product information CAS Number:

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