NVP-BSK805 trihydrochloride - CAS# 2320258-95-3 Size:Contact [email protected] for quotation After oral or intraperitoneal dosing

After oral or intraperitoneal dosing in mice

Chemical Name: (S)-2-hydroxy-3-methyl-N-((S)-1-(((S)-5-methyl-6-oxo-6

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC2=CNC3=CC=CC=C23)NC(=O)[C@H](CC2C=CC=CC=2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@H](CO)[C@@H](C)O)NC(=O)[C@H](N)CC1C=CC=CC=1

ESI-09 shows an increased potency with an apparent IC50 of 10 µM

Smiles: NC(=N)C1=CC2=CC=C(C=C2S1)OC(=O)C1=CC=CS1

NVP-BSK805 trihydrochloride - CAS# 2320258-95-3 Size:Contact [email protected] for quotation After oral or intraperitoneal dosingNVP BSK805 trihydrochloride trihydrochloride is an ATP competitive JAK2 inhibitor, with IC50s of 0. 48 nM, 31. 63 nM, 18. 68 nM, and 10. 76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively. Product information CAS Number: 2320258 95 3 Molecular Weight: 599. 93 Formula: C27H31Cl3F2N6O Chemical Name: 4 (2, 6 difluoro 4 (3 (1 (piperidin 4 yl) 1H pyrazol 4 yl)quinoxalin 5 yl)benzyl)morpholine trihydrochloride Smiles: Cl.