2-Deoxy-D-glucose 6-phosphate disodium ne-1 4-diylbis(phosphonate) indicating that Brusatol (NSC 172924)

indicating that Brusatol (NSC 172924) is able to reach the tumor tissue and inhibit the Nrf2 pathway

C2HF3O2/c1-7-30(5)49(76-54(90)36(15-19-44(65)79)69-57(93)40(24-48(85)86)73-55(91)38(22-29(3)4)71-51(87)33(63)26-100)60(96)66-25-45(80)67-34(16-20-46(81)82)52(88)72-39(23-32-12-10-9-11-13-32)56(92)68-35(14-18-43(64)78)53(89)74-42(28-102)59(95)77-50(31(6)8-2)61(97)75-41(27-101)58(94)70-37(62(98)99)17-21-47(83)84

in KBM-5 cells

TRPV1 functions as a molecular integrator of nociceptive stimuli

5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1

2-Deoxy-D-glucose 6-phosphate disodium ne-1 4-diylbis(phosphonate) indicating that Brusatol (NSC 172924)2 Deoxy D glucose 6 phosphate disodium, a derivative of 2 Deoxy D glucose, is produced in mammalian cells by the action of hexokinase on 2 DG. 2 Deoxy D glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase. Product information CAS Number: 33068 19 8 Molecular Weight: 267. 13 Formula: C6H13NaO8P Chemical Name: [(2,3,4 trihydroxy 6 oxohexyl)oxy]phosphonic acid sodium