Z-DQMD-FMK 17517 In contrast to the reported

In contrast to the reported HDAC6-selective inhibitors

and maintenance of immune functions

Chemical Name: 2-amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2

4-Tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-nicotinoylquinoline

2 μM for A

Z-DQMD-FMK 17517 In contrast to the reportedInhibition of caspase 3 processing by Z DQMD FMK (Z Asp(OMe) Gln Met Asp(OMe) fluoromethylketone) did not restore cell number in the zinc deficient group, but resulted in processing of full length PKC to a 56 kDa fragment1. The inhibitory effect of specific caspase inhibitors (Z DQMD FMK, Z IETD FMK and Z LEHD FMK) suggests that the MG132 induced apoptotic cell death and depletion of GSH in SCLC cells are mediated by both activation of caspase 8 and