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to the α-1 receptors on the membrane of vascular smooth muscle cells
Formula: C25H29N3O3
and consequently
Chemical Name: 2-benzyl-4
3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid hydrochloride
PP2 - CAS# 172889-27-9 Catalog No.:M9704-10 to the α-1 receptors onPP2, also known as AG 1879, is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP 70 (100 M) and JAK2 (50 M). Despite its extensive use as a Src selective inhibitor, recent research has shown that PP2 is non selective and inhibits many
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