Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
4-O-Methyl honokiol (20 μM) increases the expression
Smiles: O[C@H]1CN(CC1)C1N=CC(=CC=1C1C=CNN=1)C(=O)NC1C=CC(=CC=1)OC(F)(F)Cl
InChi: InChI=1S/C25H34N8O/c1-15-8-9-17(24(34)28-18-6-4-3-5-7-18)14-33(15)22-13-20(29-25(27-2)30-22)16-10-11-19-21(12-16)31-32-23(19)26/h10-13
Formula: C24H32O4S
Smiles: CCOC(=O)C(C)OC1=CC=CC2=C1C=CN(CC(=O)NC1=CC3OCCOC=3C=C1)C2=O
AC-4-130 Catalog No.:M31939-C 4-O-Methyl honokiol (20 μM) increasesAC 4 130 is a potent STAT5 SH2 domain inhibitor. AC 4 130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5 dependent gene transcription. AC 4 130 induces cell cycle arrest and apoptosis in FLT3 ITD driven leukemic cells. AC 4 130 has anti cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML). Product information CAS Number: 1834571 82 2
US$ 56.00
US$ 135.00
US$ 349.50
US$ 524.00
US$ 150.00
US$ 1499.00
US$ 874.00
US$ 98.00
US$ 23.95
US$ 1449.99
US$ 56.00
US$ 125.00
US$ 949.00
US$ 1199.00