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Formula: C22H27N5O4
which leads to a conformational change in the EED H3K27me3-binding pocket and prevents the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2)
CAS Number: 76823-03-5
confirming that potentiation was due to DNA-PK inhibition
inhibits growth of Staphyloccus
Cobicistat - CAS# 1004316-88-4 rase Formula: C22H27N5O4Cobicistat, also known as GS9350, is an approved drug for use in the treatment of infection with the human immunodeficiency virus (HIV). Like ritonavir (Norvir), cobicistat is of interest not for its anti HIV properties, but rather its ability to inhibit liver enzymes that metabolize other medications used to treat HIV, notably elvitegravir, an HIV integrase inhibitor currently under investigation itself. By combining cobicistat with elvitegravir,