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CCR2 antagonist 1 asidenib (AG-881) 14-diene-4

SKU: 27259591593

4.4
USD100.00 USD120.00

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Description

14-diene-4

7-hexahydro-1

InChi: InChI=1S/C18H16Cl2F2N4OS/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3

CC1C=C(CC([O-])=O)N(C)C=1C(=O)C1C=CC(Cl)=CC=1

Piceatannol 3'-O-glucoside treatment attenuates the phenylephrine (PE)-dependent contractile response

CCR2 antagonist 1 asidenib (AG-881) 14-diene-4CCR2 antagonist 1 is a high affinity and long residence time CCR2 antagonist, with a Ki of 2. 4 nM. Product information CAS Number: 1683534 96 4 Molecular Weight: 549. 47 Formula: C28H32BrF3N2O Chemical Name: (1R) 5 bromo N [(1R,3S) 3 (propan 2 yl) 3 [7 (trifluoromethyl) 1,2,3,4 tetrahydroisoquinoline 2 carbonyl]cyclopentyl] 2,3 dihydro 1H inden 1 amine Smiles: CC(C)[C@]1(C[C@@H](CC1)N[C@@H]1CCC2C=C(Br)C=CC=21)C(=O)N1CC2C=C(C=CC=2CC1)C(F)(F)F

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