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166518-60-1
3 μM and causes parallel enhancement of PGE2 greater than PGF2 alpha greater than 6-keto-PGF1 alpha production
21)27-14-4-1-11(2-5-14)15-7-8-22-17(25-15)24-13-3-6-16-12(9-13)10-23-26-16/h1-10H
InChiKey: NQNAQPVPGUVZAF-UHFFFAOYSA-N
Chemical Name: 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-1
Astemizole Catalog No.:M18088-C 166518-60-1Astemizole (R 43512), a second generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1 receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0. 9 nM. Astemizole has antipruritic effects. Product information CAS Number: 68844 77 9 Molecular Weight: 458. 57 Formula: C28H31FN4O Chemical Name: 1 [(4 fluorophenyl)methyl] N {1 [2 (4