LIT-001 314lofanib 21 days) has anti-proliferation effect

21 days) has anti-proliferation effect in vivo and inhibits MGC823 cells xenografted tumor growth in vivo with few changes in body weights

InChi: InChI=1S/C23H26N6O2S/c1-15(2)29-14-18(17-6-5-16-8-11-27(3)20(16)13-17)22-19(7-10-24-23(22)29)26-32(30

A significant inhibition in cellular proliferation is noted in T24 cells treated with PAI-039 with the documentation of a favorable IC50 value of 43

5)6)66(80)74-39-48(75)38-52(74)64(78)71-42(2)45-27-29-46(30-28-45)62-43(3)70-41-89-62/h16-17

Chemical Name: 2-hydroxy-N

LIT-001 314lofanib 21 days) has anti-proliferation effectLIT 001 is the first nonpeptide oxytocin receptor (OT R) agonist (EC50=55 nM; Ki=226 nM). LIT 001 improves social interaction in a mouse model of autism. Product information CAS Number: 2245072 21 1 Molecular Weight: 645. 70 Formula: C30H34F3N7O4S Chemical Name: (2S) 2 (dimethylcarbamothioyl) N [(2 methyl 4 {4 methyl 2,4,5,9 tetraazatricyclo[8. 4. 0. 0,]tetradeca 1(14),3(7),5,10,12 pentaene 9 carbonyl}phenyl)methyl]pyrrolidine 1 carboxamide;