Vat-Cit-PAB-Monomethyl Dolastatin 10 em manganese TRAP 5bOX and TRAP 5aOX

TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM

InChi: InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24

contrasting with the stimulation by NO

RK-33 binds to DDX3 and abrogates its activity

CC1C2=CC3=NC(=CC4=NC(=CC5[N-]C(C=C([N-]2)C=1CCC([O-])=O)=C(CCC([O-])=O)C=5C)C(C=C)=C4C)C(C=C)=C3C

Vat-Cit-PAB-Monomethyl Dolastatin 10 em manganese TRAP 5bOX and TRAP 5aOXVat Cit PAB Monomethyl Dolastatin 10 is a drug linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat Cit PAB. Product information CAS Number: 1415329 13 3 Molecular Weight: 1176. 51 Formula: C60H93N11O11S Chemical Name: {4 [(2S) 2 [(2S) 2 amino 3 methylbutanamido] 5 (carbamoylamino)pentanamido]phenyl}methyl N [(1S) 1 {[(1S) 1 {[(3R,4S,5S) 3 methoxy 1 [(2R)