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1'-cyclopropane]oxy}pyridin-3-yl)-4
Lifitegrast (SAR 1118) inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1)
whereas the cell cycle progression of the nonsensitive cell lines Raji and Jurkat remains unaffected
In various solid and hematological tumor cell lines
In an assay using recombinant human PLK4
m-PEG5-Hydrazide ndol-3-yl)acetate 1'-cyclopropane]oxy}pyridin-3-yl)-4m PEG5 Hydrazide is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1449390 65 1 Molecular Weight: 294. 34 Formula: C12H26N2O6 Chemical Name: 2,5,8,11,14 pentaoxaheptadecane 17 hydrazide Smiles: COCCOCCOCCOCCOCCC(=O)NN InChiKey: HLJLUGJWPIZOAX UHFFFAOYSA N InChi: InChI=1S C12H26N2O6 c1 16 4 5 18 8 9 20 11 10 19 7 6 17 3 2 12(15)14 13 h2 11,13H2,1H3,(H,14,15) Technical Data Appearance: Solid Power
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