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ACT-132577 Size:Solid 10 mg InChiKey: MIIIKWNQFDQJGS-GIJPFRRLSA-N

SKU: 22798519880

4.4
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Description

InChiKey: MIIIKWNQFDQJGS-GIJPFRRLSA-N

Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4

Schächtele C

NVP-BEZ235 and NVP-BGT226

MPEP elevates accumbal dopamine and glycine levels

ACT-132577 Size:Solid 10 mg InChiKey: MIIIKWNQFDQJGS-GIJPFRRLSA-NAprocitentan, also known as ACT 132577, is an endothelin receptor antagonist and an pharmacologically active metabolite of macitentan. Aprocitentan antagonized the specific binding of ET 1 on membranes of cells overexpressing ET(A) and ET(B) receptors and blunted ET 1 induced calcium mobilization in various natural cell lines, with inhibitory constants within the nanomolar range. Product information CAS Number: 1103522 45 7 Molecular Weight: 546. 19

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