Abaloparatide TFA o-PEG3-alcohol 121569-61-7

121569-61-7

Formula: C21H19F3N4O4

The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease

and tumor resistance to a variety of antineoplastic agents

InChi: InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26

Abaloparatide TFA o-PEG3-alcohol 121569-61-7Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue selected to be a potent and selective activator of the PTHR1 signaling pathway. Abaloparatide TFA enhances Gs cAMP signaling (EC50 of 0. 3 nM) and arrestin recruitment (EC50 of 0. 9 nM) in MC3T3 E1 osteoblast cells. Product information Chemical Name: Ala Val Ser Glu His Gln Leu Leu His Asp Lys Gly Lys Ser Ile Gln Asp Leu Arg Arg Arg Glu Leu Leu Glu Lys Leu Leu {Aib}