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ML281 is selectively toxic to KRAS-dependent cancer cell lines
InChiKey: HWKROQUZSKPIKQ-MRXNPFEDSA-N
similar to that of metronidazole
Inhibition of PKC beta in B-cells results in prevention of NF-kB-mediated signaling and down regulation of NF-kB target genes
It has protective and curative effects against B
Seco-Duocarmycin TM Size:2mg solid ML281 is selectively toxic toSeco Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody drug conjugates (ADC). Product information CAS Number: 236102 87 7 Molecular Weight: 448. 47 Formula: C25H24N2O6 Chemical Name: (1S) 1 (hydroxymethyl) 3 (5, 6, 7 trimethoxy 1H indole 2 carbonyl) 1H, 2H, 3H benzo[e]indol 5 ol Smiles: