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RRx-001 7464 Feng Y et al

SKU: 20142523968

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Description

Feng Y et al

InChi: InChI=1S/C27H30O15/c1-37-17-4-11(2-3-13(17)30)16-7-15(32)20-14(31)5-12(6-18(20)40-16)39-25-23(22(34)21(33)19(8-28)41-25)42-26-24(35)27(36

Microsome metabolism studies and rat pharmacokinetic analysis suggests significantly more rapid metabolism of PG01 than SF-03

CAS Number: 1612888-66-0

approximately 50-80% of the cell population is undergoing apoptosis

RRx-001 7464 Feng Y et alRRx 001, a hypoxia selective epigenetic agent and studied as a radio and chem sensitizer, triggers apoptosis and overcomes drug resistance in myeloma. RRx 001 exhibits potent anti tumor activity with minimal toxicity. RRx 001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP . RRx 001 is a potent inhibitor of G6PD and shows potent antimalarial activity. Product information CAS Number: 925206 65 1 Molecular Weight: 268. 02

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