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The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues)
HL-60 (TP53 null)
Formula: C16H18O9
CH4O3S/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20
InChiKey: QQHMKNYGKVVGCZ-UHFFFAOYSA-N
S-6123 1-C2-NH2 hydrochloride The cyclosporin is acylated onS 6123 is a potent antimicrobial compound of the oxazolidinone series. S 6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis. Product information CAS Number: 87508 45 0 Molecular Weight: 272. 28 Formula: C10H12N2O5S Chemical Name: 4 [(5R) 5 (hydroxymethyl) 2 oxo 1,3 oxazolidin 3 yl]benzene 1 sulfonamide Smiles: NS(=O)(=O)C1C=CC(=CC=1)N1C[C@H](CO)OC1=O InChiKey: QVDDLNAGDYFFOJ MRVPVSSYSA N InChi: InChI=1S C10H12N2O5S c11
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