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N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
Formula: C14H20BrN4NaO12PS
CAS Number: 38748-32-2
Formula: C19H19NO3
InChiKey: TVMXJQZBKOMFQK-OOARYINLSA-L
KDM5A-IN-1 Size:Contact [email protected] for quotation N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamideKDM5A IN 1 is a potent, orally bioavailable pan histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A IN 1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B). Product information CAS Number: 1905481 36 8 Molecular Weight: 290. 36 Formula: C15H22N4O2 Chemical Name: N [(3R) 1 [3 (propan 2 yl) 1H
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