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Thalidomide is a potent costimulator of primary human T cells in vitro
Topiramate is used to treat epilepsy in children and adults
An introductory study
(2005) Cardiovasc Drug Rev
Similarly in the proliferation assay
Lometrexol hydrate - CAS# 1435784-14-7 Size:2mg solid Thalidomide is a potent costimulatorLometrexol hydrate (DDATHF hydrate), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine
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